Hi @slin25
Thank you for this interesting question.
I never heard about a routine optimizing the mesh for computation time. I know the Defrost team worked on Control Design, i.e. an optimization process of robot shape so that the simulation “converges faster and with reduced oscillations to a desired equilibrium state”.
To run several SOFA simulations, they are using the sofa-launcher application available in SOFA.
I hope this answers your question.
Best wishes,
Hugo